基于细胞外囊泡的液体活检的先进纳米技术

核心信息

• 论文英文标题: Advanced Nanotechnologies for Extracellular Vesicle-Based Liquid Biopsy
• 期刊: Adv Sci
• 发表年份: 2021
• DOI: 10.1002/advs.202102789
• PMID/PMCID: 34463056; PMC8529441

研究概览

Extracellular vesicles (EVs) are emerging as a new source of biomarkers in liquid biopsy because of their wide presence in most body fluids and their ability to load cargoes from disease-related cells. Owing to the crucial role of EVs in disease diagnosis and treatment, significant efforts have been made to isolate, detect, and analyze EVs with high efficiency.

核心发现

Extracellular vesicles (EVs) are emerging as a new source of biomarkers in liquid biopsy because of their wide presence in most body fluids and their ability to load cargoes from disease-related cells.

Owing to the crucial role of EVs in disease diagnosis and treatment, significant efforts have been made to isolate, detect, and analyze EVs with high efficiency.

A recent overview of advanced EV detection nanotechnologies is discussed here.

First, several key challenges in EV-based liquid biopsies are introduced.

Echo Biotech 角色

Echo Biotech contributed EV isolation and purification; the study also used or cited Exosupur®.

关联平台: Exoomics®, Research Reagents & Tools

关联服务与能力: EV Isolation & Purification, Research Reagent / Product Supply

关联产品或试剂: Exosupur® EV Isolation/Purification Kit

参考文献

原始论文: Advanced Nanotechnologies for Extracellular Vesicle-Based Liquid Biopsy Advanced Science. 2021. DOI: 10.1002/advs.202102789. PMID/PMCID: 34463056; PMC8529441.