年龄和性别与血浆EVs和蛋白质富集组分特征的关系
核心信息
- 论文英文标题: Associations of age and sex with characteristics of extracellular vesicles and protein-enriched fractions of blood plasma
- 期刊: Aging Cell
- 发表年份: 2024
- DOI: 10.1111/acel.14356
- PMID/PMCID: 39373063; PMC11709091
研究概览
This study aims to fill this gap by evaluating how these factors influence the particle count and proteomic profiles of plasma EV preparations and corresponding protein fractions. They carry biological molecules reflecting the physiological and pathological states of their source cells and tissues, showing potential as biomarkers.
核心发现
Extracellular vesicles (EVs) are nanosized particles that are released by various cell types and play vital roles in intercellular communication.
They carry biological molecules reflecting the physiological and pathological states of their source cells and tissues, showing potential as biomarkers.
However, the impact of demographic factors like age and sex on the properties of blood plasma EVs remains underexplored.
This study aims to fill this gap by evaluating how these factors influence the particle count and proteomic profiles of plasma EV preparations and corresponding protein fractions.
Echo Biotech 角色
血浆外泌体与血浆DIA蛋白质组
关联平台: Exoomics®
关联服务与能力: EV Proteomics
关联产品或试剂: 无明确产品引用
参考文献
原始论文: Associations of age and sex with characteristics of extracellular vesicles and protein-enriched fractions of blood plasma Aging cell. 2024. DOI: 10.1111/acel.14356. PMID/PMCID: 39373063; PMC11709091.