自噬性细胞外囊泡（AEVs）与外泌体截然不同，在病毒感染中起着至关重要的作用

核心信息

• 论文英文标题: Autophagic extracellular vesicles (AEVs) are distinct from exosomes and play crucial roles in viral infections
• 期刊: Nat Commun
• 发表年份: 2025
• DOI: 10.1038/s41467-025-67860-9
• PMID/PMCID: 41423474; PMC12852855

研究概览

Emerging evidence indicates important interconnections between autophagy and the secretion of small extracellular vesicles. However, our understanding of these secretory vesicles remains incomplete.

核心发现

Emerging evidence indicates important interconnections between autophagy and the secretion of small extracellular vesicles.

However, our understanding of these secretory vesicles remains incomplete.

Here, we identify a subtype of small extracellular vesicles, termed autophagic extracellular vesicles (AEVs), which are distinct from exosomes.

Extracellular AEVs characterized by a size less than 100 nm exhibit increased secretion when the autophagy response is induced.

Echo Biotech 角色

单囊泡膜蛋白质组PBA检测分析

关联平台: Exoomics®

关联服务与能力: EV Proteomics

关联产品或试剂: 无明确产品引用

参考文献

原始论文: Autophagic extracellular vesicles (AEVs) are distinct from exosomes and play crucial roles in viral infections Nature communications. 2025. DOI: 10.1038/s41467-025-67860-9. PMID/PMCID: 41423474; PMC12852855.