一种用于内脏器官的无电池纳米流体细胞内递送贴片
核心信息
- 论文英文标题: A battery-free nanofluidic intracellular delivery patch for internal organs
- 期刊: Nature
- 发表年份: 2025
- DOI: 10.1038/s41586-025-08943-x
- PMID/PMCID: 40307560; 8033518
研究概览
The targeted delivery of therapeutics to internal organs to, for example, promote healing or apoptosis holds promise in the treatment of numerous diseases1-4. Currently, the prevailing delivery modality relies on the circulation; however, this modality has substantial efficiency, safety and/or controllability limitations5-9.
核心发现
The targeted delivery of therapeutics to internal organs to, for example, promote healing or apoptosis holds promise in the treatment of numerous diseases1-4.
Currently, the prevailing delivery modality relies on the circulation; however, this modality has substantial efficiency, safety and/or controllability limitations5-9.
Here we report a battery-free, chipless, soft nanofluidic intracellular delivery (NanoFLUID) patch that provides enhanced and customized delivery of payloads in targeted internal organs.
The chipless architecture and the flexible nature of thin functional layers facilitate integration with internal organs.
Echo Biotech 角色
引用：Exosupur分离组织外泌体；实际提供服务：细胞上清和乳腺肿瘤组织外泌体分离表征
关联平台: Exoomics®, Research Reagents & Tools
关联服务与能力: Tissue EV Isolation & Purification, Cell-Culture Supernatant EV Isolation & Purification, EV Basic Characterization (TEM/NTA/WB), Research Reagent / Product Supply
关联产品或试剂: Exosupur® EV Isolation/Purification Kit
参考文献
原始论文: A battery-free nanofluidic intracellular delivery patch for internal organs Nature. 2025. DOI: 10.1038/s41586-025-08943-x. PMID/PMCID: 40307560; 8033518.