生物信息学分析揭示了烟雾病中免疫细胞浸润landscape和新的免疫相关生物标志物

核心信息

• 论文英文标题: Bioinformatics analysis reveals the landscape of immune cell infiltration and novel immune-related biomarkers in moyamoya disease
• 期刊: Front Genet
• 发表年份: 2023
• DOI: 10.3389/fgene.2023.1101612
• PMID/PMCID: 37265961; PMC10230076

研究概览

Objective: This study aimed to identify immune infiltration characteristics and new immunological diagnostic biomarkers in the cerebrovascular tissue of moyamoya disease (MMD) using bioinformatics analysis. These immune-related genes and cells may provide novel insights for immunotherapy in the future.

核心发现

Objective: This study aimed to identify immune infiltration characteristics and new immunological diagnostic biomarkers in the cerebrovascular tissue of moyamoya disease (MMD) using bioinformatics analysis.

Methods: GSE189993 and GSE141022 were downloaded from the GEO database.

Differentially expressed gene and PPI analysis were performed.

After performing WGCNA, the most significant module associated with MMD was obtained.

Echo Biotech 角色

Echo Biotech's specific contribution should be verified from the full text or internal project record.

关联平台: To Be Verified

关联服务与能力: Role Not Identified

关联产品或试剂: 无明确产品引用

参考文献

原始论文: Bioinformatics analysis reveals the landscape of immune cell infiltration and novel immune-related biomarkers in moyamoya disease Front Genet. 2023. DOI: 10.3389/fgene.2023.1101612. PMID/PMCID: 37265961; PMC10230076.