检测与心脏外泌体基因特征相关的急性心肌梗死早期生物标志物:外泌体溯源研究

核心信息

  • 论文英文标题: Detecting early-warning biomarkers associated with heart-exosome genetic-signature for acute myocardial infarction: A source-tracking study of exosome
  • 期刊: J Cell Mol Med
  • 发表年份: 2024
  • DOI: 10.1111/jcmm.18334
  • PMID/PMCID: 38661439; PMC11044819

研究概览

The genetic information of plasma total-exosomes originating from tissues have already proven useful to assess the severity of coronary artery diseases (CAD). However, plasma total-exosomes include multiple sub-populations secreted by various tissues.

核心发现

The genetic information of plasma total-exosomes originating from tissues have already proven useful to assess the severity of coronary artery diseases (CAD).

However, plasma total-exosomes include multiple sub-populations secreted by various tissues.

Only analysing the genetic information of plasma total-exosomes is perturbed by exosomes derived from other organs except the heart.

We aim to detect early-warning biomarkers associated with heart-exosome genetic-signatures for acute myocardial infarction (AMI) by a source-tracking analysis of plasma exosome.

Echo Biotech 角色

外泌体分离试剂盒exosupur

关联平台: Exoomics®, Research Reagents & Tools

关联服务与能力: Biofluid EV Isolation & Purification, Research Reagent / Product Supply

关联产品或试剂: Exosupur® EV Isolation/Purification Kit

参考文献

原始论文: Detecting early-warning biomarkers associated with heart-exosome genetic-signature for acute myocardial infarction: A source-tracking study of exosome J Cell Mol Med. 2024. DOI: 10.1111/jcmm.18334. PMID/PMCID: 38661439; PMC11044819.