肺炎克雷伯菌通过外膜囊泡OMVs传播毒力和耐药基因：促进耐碳青霉烯类高致病性肺炎克雷伯菌CR-hvKp产生的重要质粒转移机制

核心信息

• 论文英文标题: Dissemination of Virulence and Resistance Genes among Klebsiella pneumoniae Via Outer Membrane Vesicle (OMVs): An Important Plasmid Transfer Mechanism to Promote the Emergence of Carbapenem-resistant Hypervirulent Klebsiella pneumoniae (CR-hvKp)
• 期刊: Transbound Emerg Dis
• 发表年份: 2022
• DOI: 10.1111/tbed.14615
• PMID/PMCID: 35679514

研究概览

In this study, we performed complete genome sequencing of two K. The CRK3022 acquired the virulence plasmid phvK2115 could become a CR-hvKp strain.

核心发现

Klebsiella pneumoniae is well-known opportunistic enterobacteria involved in complex clinical infections in humans and animals.

The domestic animals might be a source of the multidrug-resistant virulent K.

pneumoniae to humans.

pneumoniae infections in domestic animals are considered as an emergent global concern.

Echo Biotech 角色

NTA

关联平台: Exoomics®

关联服务与能力: EV Basic Characterization (TEM/NTA/WB)

关联产品或试剂: 无明确产品引用

参考文献

原始论文: Dissemination of Virulence and Resistance Genes among Klebsiella pneumoniae Via Outer Membrane Vesicle (OMVs): An Important Plasmid Transfer Mechanism to Promote the Emergence of Carbapenem-resistant Hypervirulent Klebsiella pneumoniae (CR-hvKp) Transbound Emerg Dis. 2022. DOI: 10.1111/tbed.14615. PMID/PMCID: 35679514.