精神刺激性甲基苯丙胺戒断患者的动态免疫和外泌体转录组应答

核心信息

• 论文英文标题: Dynamic immune and exosome transcriptomic responses in patients undergoing psychostimulant methamphetamine withdrawal
• 期刊: Front Cell Neurosci
• 发表年份: 2022
• DOI: 10.3389/fncel.2022.961131
• PMID/PMCID: 36238831; PMC9550894

研究概览

Herein, we investigated the peripheral cytokines and exosomal transcriptome regulatory networks in the patients with METH use disorders (MUDs) undergoing withdrawal. However, the pathogenesis remains largely unknown.

核心发现

Methamphetamine (METH) addiction and withdrawal cause serious harm to both the immune system and nervous system.

However, the pathogenesis remains largely unknown.

Herein, we investigated the peripheral cytokines and exosomal transcriptome regulatory networks in the patients with METH use disorders (MUDs) undergoing withdrawal.

Twenty-seven cytokines were simultaneously assessed in 51 subjects, including 22 at the acute withdrawal (AW) stage and 29 at the protracted withdrawal (PW) stage, and 31 age and gender-matched healthy controls (HCs).

Echo Biotech 角色

血浆外泌体长链测序，与EA54同一项目，全转数据拆分发表

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关联产品或试剂: Exosupur® EV Isolation/Purification Kit

参考文献

原始论文: Dynamic immune and exosome transcriptomic responses in patients undergoing psychostimulant methamphetamine withdrawal Front Cell Neurosci. 2022. DOI: 10.3389/fncel.2022.961131. PMID/PMCID: 36238831; PMC9550894.