单核细胞增生李斯特菌通过操纵巨噬细胞外泌体ncRNAs调节巨噬细胞炎症反应以促进其细胞内存活

核心信息

• 论文英文标题: Listeria monocytogenes Modulates Macrophage Inflammatory Responses to Facilitate Its Intracellular Survival by Manipulating Macrophage-Derived Exosomal ncRNAs
• 期刊: Microorganisms
• 发表年份: 2025
• DOI: 10.3390/microorganisms13020410
• PMID/PMCID: 40005775; PMC11858176

研究概览

Utilizing bioinformatics and dual-luciferase reporter assays, we identified two potential binding sites between lncRNA Rpl13a-213 and miR-132-3p. Listeria monocytogenes (L.

核心发现

Exosomes are nanoscale vesicles secreted by cells that play vital regulatory roles in intercellular communication and immune responses.

Listeria monocytogenes (L.

Monocytogenes, LM) is a notable Gram-positive intracellular parasitic bacterium that infects humans and diverse animal species.

However, the specific biological function of exosomes secreted by macrophages during L.

Echo Biotech 角色

Exosupur排阻柱

关联平台: Exoomics®, Research Reagents & Tools

关联服务与能力: Cell-Culture Supernatant EV Isolation & Purification, Research Reagent / Product Supply

关联产品或试剂: Exosupur® EV Isolation/Purification Kit

参考文献

原始论文: Listeria monocytogenes Modulates Macrophage Inflammatory Responses to Facilitate Its Intracellular Survival by Manipulating Macrophage-Derived Exosomal ncRNAs Microorganisms. 2025. DOI: 10.3390/microorganisms13020410. PMID/PMCID: 40005775; PMC11858176.