骨肉瘤血浆外泌体lncRNA和circRNA及mRNA表达图谱

核心信息

• 论文英文标题: Long non-coding RNA and circular RNA and coding RNA profiling of plasma exosomes of osteosarcoma by RNA seq
• 期刊: Sci Data
• 发表年份: 2023
• DOI: 10.1038/s41597-023-02295-9
• PMID/PMCID: 37349312; PMC10287625

研究概览

Osteosarcoma (OS) is a primary bone tumor with high malignancy and the mechanism of hematogenous metastasis in OS is still not clear. This data set provides a significant resource for relevant researchers to excavate potential dysregulated lncRNAs, circRNAs and mRNAs of plasma exosomes in OS versus normal conditions.

核心发现

Osteosarcoma (OS) is a primary bone tumor with high malignancy and the mechanism of hematogenous metastasis in OS is still not clear.

The plasma exosomes derived from osteosarcoma play a key role in the process of tumor metastasis.

Here, we established RNA-seq dataset for lncRNAs, circRNAs and mRNAs in plasma exosomes from 10 OS patients and 5 healthy donors.

52 Gb of clean data was obtained.

Echo Biotech 角色

血浆外泌体分离鉴定及长链RNA测序分析

关联平台: Exoomics®

关联服务与能力: Biofluid EV Isolation & Purification, EV Basic Characterization (TEM/NTA/WB), EV lncRNA/mRNA Sequencing

关联产品或试剂: 无明确产品引用

参考文献

原始论文: Long non-coding RNA and circular RNA and coding RNA profiling of plasma exosomes of osteosarcoma by RNA seq Sci Data. 2023. DOI: 10.1038/s41597-023-02295-9. PMID/PMCID: 37349312; PMC10287625.