来自循环小细胞外囊泡的 miRNA 作为鼻咽癌的诊断生物标志物

核心信息

• 论文英文标题: miRNAs derived from circulating small extracellular vesicles as diagnostic biomarkers for nasopharyngeal carcinoma
• 期刊: Cancer Sci
• 发表年份: 2021
• DOI: 10.1111/cas.14883
• PMID/PMCID: 33728743; PMC8177774

研究概览

This study was designed to evaluate the circulating sEV-derived miRNAs as biomarkers for the diagnosis of nasopharyngeal carcinoma (NPC). The model based on the 3 sEV-derived miRNAs could potentially act as an alternative or complementary approach for diagnosing NPC.

核心发现

The microRNAs (miRNAs) in circulating small extracellular vesicles (sEVs) have been suggested as potential biomarkers in cancer diagnosis.

This study was designed to evaluate the circulating sEV-derived miRNAs as biomarkers for the diagnosis of nasopharyngeal carcinoma (NPC).

We compared the miRNA profiles in plasma-derived sEVs between 16 patients with NPC and 5 healthy controls (HCs).

A distinct set of miRNAs that were differentially expressed between patients with NPC and HCs was determined by means of integrative bioinformatics approaches.

Echo Biotech 角色

血浆外泌体miRNA测序分析

关联平台: Exoomics®

关联服务与能力: EV miRNA Profiling / Sequencing

关联产品或试剂: 无明确产品引用

参考文献

原始论文: miRNAs derived from circulating small extracellular vesicles as diagnostic biomarkers for nasopharyngeal carcinoma Cancer Sci. 2021. DOI: 10.1111/cas.14883. PMID/PMCID: 33728743; PMC8177774.