一种调控骨折组织外泌体lncRNA-mRNA促进间充质干细胞增殖和迁移的新方法
核心信息
- 论文英文标题: A New Method Regulates Bone Fracture Tissue Exosome lncRNA-mRNA to Promote Mesenchymal Stem Cell Proliferation and Migration
- 期刊: Injury
- 发表年份: 2023
- DOI: 10.1016/j.injury.2023.111210
- PMID/PMCID: 38006783
研究概览
This study was to discuss the role of fracture site tissue exosomes lncRNAs-mRNAs networks on PIA promoting bone mesenchymal stem cells (BMSCs) proliferation and migration. This study was to discuss the role of fracture site tissue exosomes lncRNAs-mRNAs networks on PIA promoting bone mesenchymal stem cells (BMSCs) proliferation and migration.
核心发现
Post-injury adaptation (PIA) is a simple and convenient method to promote bone healing, but its mechanism is unclear.
This study was to discuss the role of fracture site tissue exosomes lncRNAs-mRNAs networks on PIA promoting bone mesenchymal stem cells (BMSCs) proliferation and migration.
Firstly, the effects of PIA accelerating BMSCs proliferation and migration were confirmed by rat fracture model and bone fracture environment in vitro.
Besides, the fracture site tissue exosomes were isolated and authenticated.
Echo Biotech 角色
客户自分离小鼠骨折组织外泌体长链RNA测序分析
关联平台: Exoomics®
关联服务与能力: Tissue EV Isolation & Purification, EV lncRNA/mRNA Sequencing
关联产品或试剂: 无明确产品引用
参考文献
原始论文: A New Method Regulates Bone Fracture Tissue Exosome lncRNA-mRNA to Promote Mesenchymal Stem Cell Proliferation and Migration Injury. 2023. DOI: 10.1016/j.injury.2023.111210. PMID/PMCID: 38006783.