早期肺腺癌血浆EV-miRNA谱及其诊断特征分析

核心信息

• 论文英文标题: Plasma extracellular vesicle microRNA profiling and the identification of a diagnostic signature for stage I lung adenocarcinoma
• 期刊: CANCER SCI
• 发表年份: 2021
• DOI: 10.1111/cas.15222
• PMID/PMCID: 34837453; PMC8819331

研究概览

This study examined the profile of plasma extracellular vesicle (EV)-delivered microRNAs (miRNAs) in patients with invasive stage I LUAD. This study examined the profile of plasma extracellular vesicle (EV)-delivered microRNAs (miRNAs) in patients with invasive stage I LUAD.

核心发现

At present, there is no effective noninvasive method for the accurate diagnosis of early-stage lung adenocarcinoma (LUAD).

This study examined the profile of plasma extracellular vesicle (EV)-delivered microRNAs (miRNAs) in patients with invasive stage I LUAD.

In this study, a total of 460 participants were enrolled, including 254 patients with LUAD, 76 patients with benign pulmonary nodules (BPNs), and 130 healthy control patients (HCs).

miRNA sequencing was used to analyze the EV miRNA profile of the patient plasma samples (n = 150).

Echo Biotech 角色

与EA48同一个项目--全转数据拆分发表

关联平台: Exoomics®

关联服务与能力: EV miRNA Profiling / Sequencing, EV Whole-Transcriptome Sequencing

关联产品或试剂: 无明确产品引用

参考文献

原始论文: Plasma extracellular vesicle microRNA profiling and the identification of a diagnostic signature for stage I lung adenocarcinoma CANCER SCI. 2021. DOI: 10.1111/cas.15222. PMID/PMCID: 34837453; PMC8819331.