从含细胞质液滴精子的精浆中分离外泌体与常规公猪精浆外泌体的miRNA表达模式

核心信息

• 论文英文标题: Small RNA expression patterns in seminal plasma exosomes isolated from semen containing spermatozoa with cytoplasmic droplets versus regular exosomes in boar semen
• 期刊: Theriogenology
• 发表年份: 2021
• DOI: 10.1016/j.theriogenology.2021.09.031
• PMID/PMCID: 34673403

研究概览

In this study, seminal plasma exosomes were isolated from semen containing spermatozoa with CDs and miRNA expression profiles were analyzed. Exosomes may be found in seminal plasma where they carry functional molecules to the sperm, such as microRNAs (miRNAs).

核心发现

Multiple physiological pathways are controlled by exosomes.

Exosomes may be found in seminal plasma where they carry functional molecules to the sperm, such as microRNAs (miRNAs).

Sperm cytoplasmic droplets (CDs) are remnants of cytoplasm, and their migration is a morphological characteristic of epididymal maturation.

However, miRNA expression patterns in seminal plasma exosomes found in semen containing spermatozoa with CDs versus regular exosomes in boar semen have not been examined.

Echo Biotech 角色

精浆外泌体miRNA测序分析及NTA检测

关联平台: Exoomics®

关联服务与能力: EV Basic Characterization (TEM/NTA/WB), EV miRNA Profiling / Sequencing

关联产品或试剂: 无明确产品引用

参考文献

原始论文: Small RNA expression patterns in seminal plasma exosomes isolated from semen containing spermatozoa with cytoplasmic droplets versus regular exosomes in boar semen Theriogenology. 2021. DOI: 10.1016/j.theriogenology.2021.09.031. PMID/PMCID: 34673403.