Advanced Nanotechnologies for Extracellular Vesicle-Based Liquid Biopsy

Quick Facts

• Publication title: Advanced Nanotechnologies for Extracellular Vesicle-Based Liquid Biopsy
• Journal: Adv Sci
• Year: 2021
• DOI: 10.1002/advs.202102789
• PMID/PMCID: 34463056; PMC8529441

Research overview

Extracellular vesicles (EVs) are emerging as a new source of biomarkers in liquid biopsy because of their wide presence in most body fluids and their ability to load cargoes from disease-related cells. Owing to the crucial role of EVs in disease diagnosis and treatment, significant efforts have been made to isolate, detect, and analyze EVs with high efficiency.

Key findings

Extracellular vesicles (EVs) are emerging as a new source of biomarkers in liquid biopsy because of their wide presence in most body fluids and their ability to load cargoes from disease-related cells.

Owing to the crucial role of EVs in disease diagnosis and treatment, significant efforts have been made to isolate, detect, and analyze EVs with high efficiency.

A recent overview of advanced EV detection nanotechnologies is discussed here.

First, several key challenges in EV-based liquid biopsies are introduced.

Echo Biotech Role

Echo Biotech contributed EV isolation and purification; the study also used or cited Exosupur®.

Related platforms: Exoomics®, Research Reagents & Tools

Related services and capabilities: EV Isolation & Purification, Research Reagent / Product Supply

Related products or reagents: Exosupur® EV Isolation/Purification Kit

References

Original publication: Advanced Nanotechnologies for Extracellular Vesicle-Based Liquid Biopsy Advanced Science. 2021. DOI: 10.1002/advs.202102789. PMID/PMCID: 34463056; PMC8529441.