Exosome Subpopulation Proteomics (Tumor / Neural)
Product Overview POI (proteins of interest)+ EV subpopulation research refers to capturing POI-positive EVs with immunomagnetic beads coupled to POI antibodies, followed by characterization of the cargo and functions of that EV subpopulation.
Quick Facts
- Advanced Exosome Technologies
- Services
- Product Overview POI (proteins of interest)+ EV subpopulation research refers to capturing POI-positive EVs with immunomagnetic beads coupled to POI antibodies, followed by characterization of the cargo and functions of that EV subpopulation.
Overview
Product Overview
POI (proteins of interest)+ EV subpopulation research refers to capturing POI-positive EVs with immunomagnetic beads coupled to POI antibodies, followed by characterization of the cargo and functions of that EV subpopulation.
Fine-resolution analysis of EV subpopulations helps address the challenge of EV heterogeneity more effectively, supports clarification of the biological roles of different EV subsets, and may improve the efficiency and accuracy of liquid biopsy studies.
Exosome subpopulation proteomics focuses on proteomics profiling of POI+ EV subpopulations to resolve their protein cargo, identify marker molecules associated with disease diagnosis, prognosis, or treatment response, and explore underlying molecular mechanisms. In this service, the current POIs are PD-L1 and L1CAM.
Product Overview
POI (proteins of interest)+ EV subpopulation research refers to capturing POI-positive EVs with immunomagnetic beads coupled to POI antibodies, followed by characterization of the cargo and functions of that EV subpopulation.
Applications
Multi-omics studies of PD-L1+ EV subpopulations provide important tools for cancer diagnosis, prognosis evaluation, and dissection of the tumor immunosuppressive microenvironment.
Technical Workflow and Project Workflow
Technical workflow
Technical Advantages
Novel angle: conventional studies often focus on the cargo of total EVs from circulation, tissues, or cells, while this service specifically targets POI+ EV subpopulations.
Representative Results
1. Proteomics data examples for PD-L1+ tumor and immune EV subpopulations
Representative Case Studies
1. Capturing PD-L1-positive small extracellular vesicles to dissect their subpopulation features and functions
FAQ
1. What sample types are currently accepted? Plasma/serum, tumor tissue (PD-L1+), and brain tissue (L1CAM+).
Sample Submission Recommendations
FAQ
- What service is Exosome Subpopulation Proteomics (Tumor / Neural)?
- Exosome Subpopulation Proteomics (Tumor / Neural) is an exosome technical service under the Advanced Exosome Technologies category. Product Overview POI (proteins of interest)+ EV subpopulation research refers to capturing POI-positive EVs with immunomagnetic beads coupled to POI antibodies, followed by characterization of the cargo and functions of that EV subpopulation.
- What research needs can Exosome Subpopulation Proteomics (Tumor / Neural) support?
- Exosome Subpopulation Proteomics (Tumor / Neural) can support research needs including: Product Overview; POI (proteins of interest)+ EV subpopulation research refers to capturing POI-positive EVs with immunomagnetic beads co…; Fine-resolution analysis of EV subpopulations helps address the challenge of EV heterogeneity more effectively, support….
- What does the Exosome Subpopulation Proteomics (Tumor / Neural) workflow include?
- The current page describes modules such as Product Overview, Applications, Technical Workflow and Project Workflow, Technical Advantages, and Representative Results.
- What deliverables are available for Exosome Subpopulation Proteomics (Tumor / Neural)?
- Deliverables usually include testing results, analysis data, figures, or project reports. The final format and depth should be confirmed according to the service plan, sample status, and project goals.
- How can customers discuss Exosome Subpopulation Proteomics (Tumor / Neural)?
- Customers can contact Echo Biotech with sample type, research objective, expected testing scope, and timeline requirements to confirm a suitable Exosome Subpopulation Proteomics (Tumor / Neural) service plan.