Associations of age and sex with characteristics of extracellular vesicles and protein-enriched fractions of blood plasma
Quick Facts
- Publication title: Associations of age and sex with characteristics of extracellular vesicles and protein-enriched fractions of blood plasma
- Journal: Aging Cell
- Year: 2024
- DOI: 10.1111/acel.14356
- PMID/PMCID: 39373063; PMC11709091
Research overview
This study aims to fill this gap by evaluating how these factors influence the particle count and proteomic profiles of plasma EV preparations and corresponding protein fractions. They carry biological molecules reflecting the physiological and pathological states of their source cells and tissues, showing potential as biomarkers.
Key findings
Extracellular vesicles (EVs) are nanosized particles that are released by various cell types and play vital roles in intercellular communication.
They carry biological molecules reflecting the physiological and pathological states of their source cells and tissues, showing potential as biomarkers.
However, the impact of demographic factors like age and sex on the properties of blood plasma EVs remains underexplored.
This study aims to fill this gap by evaluating how these factors influence the particle count and proteomic profiles of plasma EV preparations and corresponding protein fractions.
Echo Biotech Role
Echo Biotech contributed EV proteomics.
Related platforms: Exoomics®
Related services and capabilities: EV Proteomics
References
Original publication: Associations of age and sex with characteristics of extracellular vesicles and protein-enriched fractions of blood plasma Aging cell. 2024. DOI: 10.1111/acel.14356. PMID/PMCID: 39373063; PMC11709091.