A battery-free nanofluidic intracellular delivery patch for internal organs
Quick Facts
- Publication title: A battery-free nanofluidic intracellular delivery patch for internal organs
- Journal: Nature
- Year: 2025
- DOI: 10.1038/s41586-025-08943-x
- PMID/PMCID: 40307560; 8033518
Research overview
The targeted delivery of therapeutics to internal organs to, for example, promote healing or apoptosis holds promise in the treatment of numerous diseases1-4. Currently, the prevailing delivery modality relies on the circulation; however, this modality has substantial efficiency, safety and/or controllability limitations5-9.
Key findings
The targeted delivery of therapeutics to internal organs to, for example, promote healing or apoptosis holds promise in the treatment of numerous diseases1-4.
Currently, the prevailing delivery modality relies on the circulation; however, this modality has substantial efficiency, safety and/or controllability limitations5-9.
Here we report a battery-free, chipless, soft nanofluidic intracellular delivery (NanoFLUID) patch that provides enhanced and customized delivery of payloads in targeted internal organs.
The chipless architecture and the flexible nature of thin functional layers facilitate integration with internal organs.
Echo Biotech Role
Echo Biotech contributed EV isolation and purification, EV characterization; the study also used or cited Exosupur®.
Related platforms: Exoomics®, Research Reagents & Tools
Related services and capabilities: Tissue EV Isolation & Purification, Cell-Culture Supernatant EV Isolation & Purification, EV Basic Characterization (TEM/NTA/WB), Research Reagent / Product Supply
Related products or reagents: Exosupur® EV Isolation/Purification Kit
References
Original publication: A battery-free nanofluidic intracellular delivery patch for internal organs Nature. 2025. DOI: 10.1038/s41586-025-08943-x. PMID/PMCID: 40307560; 8033518.