Detecting early-warning biomarkers associated with heart-exosome genetic-signature for acute myocardial infarction: A source-tracking study of exosome
Quick Facts
- Publication title: Detecting early-warning biomarkers associated with heart-exosome genetic-signature for acute myocardial infarction: A source-tracking study of exosome
- Journal: J Cell Mol Med
- Year: 2024
- DOI: 10.1111/jcmm.18334
- PMID/PMCID: 38661439; PMC11044819
Research overview
The genetic information of plasma total-exosomes originating from tissues have already proven useful to assess the severity of coronary artery diseases (CAD). However, plasma total-exosomes include multiple sub-populations secreted by various tissues.
Key findings
The genetic information of plasma total-exosomes originating from tissues have already proven useful to assess the severity of coronary artery diseases (CAD).
However, plasma total-exosomes include multiple sub-populations secreted by various tissues.
Only analysing the genetic information of plasma total-exosomes is perturbed by exosomes derived from other organs except the heart.
We aim to detect early-warning biomarkers associated with heart-exosome genetic-signatures for acute myocardial infarction (AMI) by a source-tracking analysis of plasma exosome.
Echo Biotech Role
Echo Biotech contributed EV isolation and purification; the study also used or cited Exosupur®.
Related platforms: Exoomics®, Research Reagents & Tools
Related services and capabilities: Biofluid EV Isolation & Purification, Research Reagent / Product Supply
Related products or reagents: Exosupur® EV Isolation/Purification Kit
References
Original publication: Detecting early-warning biomarkers associated with heart-exosome genetic-signature for acute myocardial infarction: A source-tracking study of exosome J Cell Mol Med. 2024. DOI: 10.1111/jcmm.18334. PMID/PMCID: 38661439; PMC11044819.