Dissemination of Virulence and Resistance Genes among Klebsiella pneumoniae Via Outer Membrane Vesicle (OMVs): An Important Plasmid Transfer Mechanism to Promote the Emergence of Carbapenem-resistant Hypervirulent Klebsiella pneumoniae (CR-hvKp)
Quick Facts
- Publication title: Dissemination of Virulence and Resistance Genes among Klebsiella pneumoniae Via Outer Membrane Vesicle (OMVs): An Important Plasmid Transfer Mechanism to Promote the Emergence of Carbapenem-resistant Hypervirulent Klebsiella pneumoniae (CR-hvKp)
- Journal: Transbound Emerg Dis
- Year: 2022
- DOI: 10.1111/tbed.14615
- PMID/PMCID: 35679514
Research overview
In this study, we performed complete genome sequencing of two K. The CRK3022 acquired the virulence plasmid phvK2115 could become a CR-hvKp strain.
Key findings
Klebsiella pneumoniae is well-known opportunistic enterobacteria involved in complex clinical infections in humans and animals.
The domestic animals might be a source of the multidrug-resistant virulent K.
pneumoniae to humans.
pneumoniae infections in domestic animals are considered as an emergent global concern.
Echo Biotech Role
Echo Biotech contributed EV characterization.
Related platforms: Exoomics®
Related services and capabilities: EV Basic Characterization (TEM/NTA/WB)
References
Original publication: Dissemination of Virulence and Resistance Genes among Klebsiella pneumoniae Via Outer Membrane Vesicle (OMVs): An Important Plasmid Transfer Mechanism to Promote the Emergence of Carbapenem-resistant Hypervirulent Klebsiella pneumoniae (CR-hvKp) Transbound Emerg Dis. 2022. DOI: 10.1111/tbed.14615. PMID/PMCID: 35679514.