Listeria monocytogenes Modulates Macrophage Inflammatory Responses to Facilitate Its Intracellular Survival by Manipulating Macrophage-Derived Exosomal ncRNAs
Quick Facts
- Publication title: Listeria monocytogenes Modulates Macrophage Inflammatory Responses to Facilitate Its Intracellular Survival by Manipulating Macrophage-Derived Exosomal ncRNAs
- Journal: Microorganisms
- Year: 2025
- DOI: 10.3390/microorganisms13020410
- PMID/PMCID: 40005775; PMC11858176
Research overview
Utilizing bioinformatics and dual-luciferase reporter assays, we identified two potential binding sites between lncRNA Rpl13a-213 and miR-132-3p. Listeria monocytogenes (L.
Key findings
Exosomes are nanoscale vesicles secreted by cells that play vital regulatory roles in intercellular communication and immune responses.
Listeria monocytogenes (L.
Monocytogenes, LM) is a notable Gram-positive intracellular parasitic bacterium that infects humans and diverse animal species.
However, the specific biological function of exosomes secreted by macrophages during L.
Echo Biotech Role
Echo Biotech contributed EV isolation and purification; the study also used or cited Exosupur®.
Related platforms: Exoomics®, Research Reagents & Tools
Related services and capabilities: Cell-Culture Supernatant EV Isolation & Purification, Research Reagent / Product Supply
Related products or reagents: Exosupur® EV Isolation/Purification Kit
References
Original publication: Listeria monocytogenes Modulates Macrophage Inflammatory Responses to Facilitate Its Intracellular Survival by Manipulating Macrophage-Derived Exosomal ncRNAs Microorganisms. 2025. DOI: 10.3390/microorganisms13020410. PMID/PMCID: 40005775; PMC11858176.