Small RNA expression patterns in seminal plasma exosomes isolated from semen containing spermatozoa with cytoplasmic droplets versus regular exosomes in boar semen
Quick Facts
- Publication title: Small RNA expression patterns in seminal plasma exosomes isolated from semen containing spermatozoa with cytoplasmic droplets versus regular exosomes in boar semen
- Journal: Theriogenology
- Year: 2021
- DOI: 10.1016/j.theriogenology.2021.09.031
- PMID/PMCID: 34673403
Research overview
In this study, seminal plasma exosomes were isolated from semen containing spermatozoa with CDs and miRNA expression profiles were analyzed. Exosomes may be found in seminal plasma where they carry functional molecules to the sperm, such as microRNAs (miRNAs).
Key findings
Multiple physiological pathways are controlled by exosomes.
Exosomes may be found in seminal plasma where they carry functional molecules to the sperm, such as microRNAs (miRNAs).
Sperm cytoplasmic droplets (CDs) are remnants of cytoplasm, and their migration is a morphological characteristic of epididymal maturation.
However, miRNA expression patterns in seminal plasma exosomes found in semen containing spermatozoa with CDs versus regular exosomes in boar semen have not been examined.
Echo Biotech Role
Echo Biotech contributed EV characterization, miRNA profiling/sequencing and bioinformatic analysis.
Related platforms: Exoomics®
Related services and capabilities: EV Basic Characterization (TEM/NTA/WB), EV miRNA Profiling / Sequencing
References
Original publication: Small RNA expression patterns in seminal plasma exosomes isolated from semen containing spermatozoa with cytoplasmic droplets versus regular exosomes in boar semen Theriogenology. 2021. DOI: 10.1016/j.theriogenology.2021.09.031. PMID/PMCID: 34673403.